Bactericidal Effects and Cytotoxicity of New Aromatic Dialdehyde Disinfectants (Ortho-phthalaldehyde)
نویسندگان
چکیده
منابع مشابه
Use of a new alginate film test to study the bactericidal efficacy of the high-level disinfectant ortho-phthalaldehyde.
OBJECTIVES To evaluate the merit of a new alginate efficacy film test to determine the bactericidal activity of the high-level disinfectant ortho-phthalaldehyde (OPA). METHODS The efficacy of OPA was investigated using a new sodium alginate surface film test against Mycobacterium chelonae NCIMB 1474 and Epping, and Pseudomonas aeruginosa NCIMB 10421 under different test conditions. RESULTS ...
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Ortho-Phthalaldehyde (OPA) has been approved for high-level sterilization of heat-sensitive medical instruments and is increasingly being used as a replacement in the healthcare industry for glutaraldehyde, a known sensitizer. Numerous case reports have been published indicating workers and patients experiencing respiratory problems, anaphylaxis, skin reactivity, and systemic antibody productio...
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Fumonisins are water soluble mycotoxins produced by the fungus Fusarium verticillioides (formerly F. moniliforme). Fumonisin B(1) (FB(1)) is a diester of propane-1,2,3-tricarboxylic acid and 2-amino-12, 16-dimethyl-3,5,10,14,15-pentahydroxyeicosane, and is the most abundant of the naturally occurring fumonisins. Upon removal of the two tricarballylic acid side chains, the structure is referred ...
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Two methods, a capacity use-dilution test and another employing geometrical dilution, are used when comparing the bactericidal and fungicidal effects of a phenolic disinfectant containing 45% (w/w) o-phenylphenol in an aqueous soap solution of linseed oil (soap content 6.5% w/v) with the corresponding effects of the same phenolic compound in an aqueous soya oil soap solution (soap content 3.5% ...
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Some studies show the uptake of disinfectants on medical devices but no studies on their cytotoxicity have been reported. This study aimed to assess that cytotoxicity in a 3-dimensional culture system using HeLa cells grown in matrices composed of collagen. Plastic materials were soaked in the use solutions of the widely used high-level disinfectants, glutaraldehyde (GA), ortho-phthalaldehyde (...
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ژورنال
عنوان ژورنال: Biocontrol Science
سال: 2011
ISSN: 1884-0205,1342-4815
DOI: 10.4265/bio.16.165